Which effects of nicotine use do most users experience? Check all that apply.

Nicotine activates the brain’s pleasure and reward systems, which can make it addictive. With repeated use, many users develop tolerance and need more nicotine to get the same effect. When they stop, withdrawal symptoms can include tiredness, so the correct choices are “Nicotine affects the pleasure centers of the brain, making it addictive,” “People have to increase their nicotine use over time to receive the same effects,” and “Stopping use leads to a tired feeling.”

AI-written and checked against the verified answer.