During the early 1800s, __________was a parcel of land that was intended to serve as a buffer between the Osage and the Western Cherokee.

Lovely’s Purchase was a parcel of land acquired in the early 1800s to create a buffer between the Osage and the Western Cherokee. The Cherokee Outlet was a different area, while the Gadsden Purchase was land bought by the United States from Mexico much later. Therefore, the best answer is Lovely’s Purchase.

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