Hemophilia is a sex-linked disorder in which a person’s blood clots very slowly or not at all. Why are males more likely to inherit hemophilia than females?

The gene for hemophilia is on the X chromosome. Males usually have one X chromosome, inherited from their mother, and one Y chromosome; if their single X carries the hemophilia allele, they can have the disorder because there is no second X to mask it. Females usually have two X chromosomes and generally need an affected allele on both to develop hemophilia, so the correct choice is “Males inherit only one X chromosome, which is from the mother.”

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