What will happen to the frequency of the recessive allele for the HbS gene when there is an outbreak of malaria?

During a malaria outbreak, people with one copy of the HbS allele have increased resistance to severe malaria. They are more likely to survive and reproduce, so the recessive HbS allele is passed on more often and its frequency tends to increase in the population. This is an example of natural selection favoring the allele in a malaria-affected environment.

AI-written and checked against the verified answer.