In the mid-1800s, one result of Manifest Destiny was that

Manifest Destiny was the belief that the United States should expand across the continent. As settlers and the U.S. government moved west, Indigenous peoples faced the loss of land, displacement, and pressure on their cultures and ways of life. The northern boundary was not set at 54°40′, and the United States did not go to war with Great Britain in 1846.

AI-written and checked against the verified answer.