What was a major difference between the Knights of Labor and the American Federation of Labor?

The Knights of Labor sought to unite workers across many occupations and included African Americans, although discrimination remained within the organization. The American Federation of Labor, led by Samuel Gompers, focused mainly on skilled workers and generally excluded Black workers from its unions. Therefore, the major difference described is that the Knights included African Americans while the AFL excluded them.

AI-written and checked against the verified answer.