2
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Question 2 • Quiz

If nondisjunction occurs and an individual survives, which disorder can occur?

Answer
A
Klinefelter syndrome
B
Robertsonian translocation
C
DiGeorge syndrome
D
fragile X syndrome

Explanation

Nondisjunction is the failure of chromosomes to separate properly during cell division, creating cells with an extra or missing chromosome. If the individual survives, a sex-chromosome number disorder such as Klinefelter syndrome (typically XXY) can result. Robertsonian translocation, DiGeorge syndrome, and fragile X syndrome are caused by other chromosome changes or mutations.

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