Which two wars resulted from rocky relations with Indigenous nations in the Carolinas?

The Tuscarora War and the Yamasee War both grew out of conflict between Carolina colonists and Indigenous nations in the region. The Powhatan Wars involved English colonists and the Powhatan Confederacy in Virginia, not the Carolinas. Therefore, the correct choices are the Tuscarora War and the Yamasee War.

AI-written and checked against the verified answer.