Mariana’s teacher has asked her to determine the type of a sample of blood. After doing some tests, she has learned that the red blood cell of the sample has no antigens on it and that the plasma contains both A and B antibodies. What is the type of the blood sample?

Type O red blood cells have neither A nor B antigens, and type O plasma contains both anti-A and anti-B antibodies. The Rh-negative sign means the cells also lack the Rh antigen. Together, these findings identify the sample as O– (choice D).

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