Grady has an inflamed knee from doing a lot of physical exercise the day before. He stops by the pharmacy to find a drug to relieve the inflammation and asks the pharmacist to recommend a drug. The pharmacist asks Grady if he has a history of peptic ulcers. Which best describes why the pharmacist needs to know this?

Aspirin is a common anti-inflammatory drug, but it can irritate the stomach lining and increase the risk of bleeding or worsening an existing peptic ulcer. This is a drug-disease interaction because the concern is between the medication and Grady’s medical condition, not between two drugs. Beta blockers are not common anti-inflammatory medications, so choices A and D are incorrect.

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